Photodynamic Therapy (PDT): PDT Mechanisms

被引：505

作者：

Allison, Ron R. ^{[1
]}

Moghissi, Keyvan ^{[2
]}

机构：

[1] 21st Century Oncol, Greenville, NC USA

[2] Yorkshire Laser Ctr, Goole DN14 6RX, East Yorkshire, England

来源：

CLINICAL ENDOSCOPY | 2013年 / 46卷 / 01期

关键词：

Photochemotherapy; Mechanisms; Photosensitizing agents; Photodynamic reaction;

D O I：

10.5946/ce.2013.46.1.24

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in oncology a photosensitizing agent is applied and then activated by a specific wavelength and energy of light. This light energy in the presence of oxygen will lead to the creation of the photodynamic reaction which is cyto and vasculo toxic. This paper will review the mechanisms of action of PDT and how they may be manipulated to improve clinical outcome in cancer patients.

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收藏

页码：24 / 29

页数：6

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