Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitors

被引：47

作者：

Skulnick, HI

Johnson, PD

Howe, WJ

Tomich, PK

Chong, KT

Watenpaugh, KD

Janakiraman, MN

Dolak, LA

McGrath, JP

Lynn, JC

Horng, MM

Hinshaw, RR

Zipp, GL

Ruwart, MJ

Schwende, FJ

Zhong, WZ

Padbury, GE

Dalga, RJ

Shiou, LH

Possert, PL

Rush, BD

Wilkinson, KF

Howard, GM

Toth, LN

Williams, MG

Kakuk, TJ

Cole, SL

Zaya, RM

Lovasz, KD

Morris, JK

Romines, KR

Thaisrivongs, S

Aristoff, PA

机构：

[1] UPJOHN CO,UPJOHN LABS,COMP AIDED DRUG DESIGN,KALAMAZOO,MI 49001

[2] UPJOHN CO,UPJOHN LABS,CHEM & BIOL SCREENING,KALAMAZOO,MI 49001

[3] UPJOHN CO,UPJOHN LABS,CANC & INFECT DIS RES,KALAMAZOO,MI 49001

[4] UPJOHN CO,UPJOHN LABS,STRUCT ANALYT & MED CHEM,KALAMAZOO,MI 49001

[5] UPJOHN CO,UPJOHN LABS,DRUG DELIVERY RES,KALAMAZOO,MI 49001

[6] UPJOHN CO,UPJOHN LABS,DRUG METAB RES,KALAMAZOO,MI 49001

[7] UPJOHN CO,UPJOHN LABS,DRUG SAFETY RES,KALAMAZOO,MI 49001

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1995年 / 38卷 / 26期

关键词：

D O I：

10.1021/jm00026a002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：4968 / 4971

页数：4

共 16 条

[11] STRUCTURE-BASED DESIGN OF NOVEL HIV PROTEASE INHIBITORS - CARBOXAMIDE-CONTAINING 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS POTENT NONPEPTIDIC INHIBITORS
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