STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS

[1] Appelt Krzysztof, 1993, Perspectives in Drug Discovery and Design, V1, P23, DOI 10.1007/BF02171654

[2] AN INHIBITOR OF THE PROTEASE BLOCKS MATURATION OF HUMAN AND SIMIAN IMMUNODEFICIENCY VIRUSES AND SPREAD OF INFECTION [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (19) : 7472 - 7476

[3] THE 3-D STRUCTURE OF HIV-1 PROTEINASE AND THE DESIGN OF ANTIVIRAL AGENTS FOR THE TREATMENT OF AIDS [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1990, 15 (11) : 425 - 430

[4] EFFECT OF THE ORAL ANTICOAGULANT, WARFARIN, ON HIV-1 REPLICATION AND SPREAD [J]. AIDS, 1993, 7 (01) : 129 - 130

[5] BISHETEROARYLPIPERAZINE REVERSE-TRANSCRIPTASE INHIBITOR IN COMBINATION WITH 3'-AZIDO-3'-DEOXYTHYMIDINE OR 2',3'-DIDEOXYCYTIDINE SYNERGISTICALLY INHIBITS HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION IN-VITRO [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (02) : 288 - 293

[6] HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE - A TARGET FOR AIDS THERAPY [J]. DRUG DEVELOPMENT RESEARCH, 1990, 21 (01) : 1 - 17

[7] GAMMILL RB, UNPUB

[8] DISCOVERY OF A NOVEL CLASS OF POTENT HIV-1 PROTEASE INHIBITORS CONTAINING THE (R)-(HYDROXYETHYL) UREA ISOSTERE [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (02) : 288 - 291

[9] ORAL ANTICOAGULANTS - MECHANISM OF ACTION, CLINICAL EFFECTIVENESS, AND OPTIMAL THERAPEUTIC RANGE [J]. CHEST, 1992, 102 (04) : S312 - S326

[10] HIV PROTEASE - A NOVEL CHEMOTHERAPEUTIC TARGET FOR AIDS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (08) : 2305 - 2314

[1] Appelt Krzysztof, 1993, Perspectives in Drug Discovery and Design, V1, P23, DOI 10.1007/BF02171654

[2] AN INHIBITOR OF THE PROTEASE BLOCKS MATURATION OF HUMAN AND SIMIAN IMMUNODEFICIENCY VIRUSES AND SPREAD OF INFECTION [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (19) : 7472 - 7476

[3] THE 3-D STRUCTURE OF HIV-1 PROTEINASE AND THE DESIGN OF ANTIVIRAL AGENTS FOR THE TREATMENT OF AIDS [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1990, 15 (11) : 425 - 430

[4] EFFECT OF THE ORAL ANTICOAGULANT, WARFARIN, ON HIV-1 REPLICATION AND SPREAD [J]. AIDS, 1993, 7 (01) : 129 - 130

[5] BISHETEROARYLPIPERAZINE REVERSE-TRANSCRIPTASE INHIBITOR IN COMBINATION WITH 3'-AZIDO-3'-DEOXYTHYMIDINE OR 2',3'-DIDEOXYCYTIDINE SYNERGISTICALLY INHIBITS HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION IN-VITRO [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (02) : 288 - 293

[6] HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE - A TARGET FOR AIDS THERAPY [J]. DRUG DEVELOPMENT RESEARCH, 1990, 21 (01) : 1 - 17

[7] GAMMILL RB, UNPUB

[8] DISCOVERY OF A NOVEL CLASS OF POTENT HIV-1 PROTEASE INHIBITORS CONTAINING THE (R)-(HYDROXYETHYL) UREA ISOSTERE [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (02) : 288 - 291

[9] ORAL ANTICOAGULANTS - MECHANISM OF ACTION, CLINICAL EFFECTIVENESS, AND OPTIMAL THERAPEUTIC RANGE [J]. CHEST, 1992, 102 (04) : S312 - S326

[10] HIV PROTEASE - A NOVEL CHEMOTHERAPEUTIC TARGET FOR AIDS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (08) : 2305 - 2314