7-HETEROARYL-1,2,3,5-TETRAHYDROIMIDAZO[2,1-B]QUINAZOLIN-2(1H)-ONE DERIVATIVES WITH CARDIAC STIMULANT ACTIVITY

被引：14

作者：

BELL, AS ^{[1
]}

CAMPBELL, SF ^{[1
]}

ROBERTS, DA ^{[1
]}

RUDDOCK, KS ^{[1
]}

机构：

[1] PFIZER LTD,CENT RES,DEPT DISCOVERY CHEM,SANDWICH,KENT,ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 09期

关键词：

D O I：

10.1021/jm00129a005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：2042 / 2049

页数：8

相关论文

共 26 条

[21] KATO T, 1974, CHEM PHARM BULL, V22, P1206
[22] KIENZLE F, 1982, EUR J MED CHEM, V17, P547
[23] A COMPARATIVE-STUDY OF THE REARRANGEMENT OF SOME 6-HALO-SUBSTITUTED AND 7-HALO-SUBSTITUTED 3-AMINO-3,4-DIHYDRO-1-HYDROXYCARBOSTYRILS IN CONCENTRATED HYDROHALIC ACIDS
MCCORD, TJ
CRAWFORD, CP
RABON, JA
GAGE, LD
WINTER, JM
DAVIS, AL
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1982, 19 (02) : 401 - 406
[24] SILKER B, 1970, EUR J PHARMACOL, V11, P269
[25] INHIBITORS OF CYCLIC-AMP PHOSPHODIESTERASE .2. STRUCTURAL VARIATIONS OF N-CYCLOHEXYL-N-METHYL-4-[(1,2,3,5-TETRAHYDRO-2-OXOIMIDAZO[2,1-B]QUINAZOLIN-7-YL)-OXY]BUTYRAMIDE (RS-82856)
VENUTI, MC
JONES, GH
ALVAREZ, R
BRUNO, JJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (02) : 303 - 318
[26] INHIBITORS OF CYCLIC-AMP PHOSPHODIESTERASE .3. SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRIDO AND IMIDAZOLYL ANALOGS OF 1,2,3,5-TETRAHYDRO-2-OXOIMIDAZO[2,1-B]QUINAZOLINE
VENUTI, MC
STEPHENSON, RA
ALVAREZ, R
BRUNO, JJ
STROSBERG, AM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (11) : 2136 - 2145