HIGHLY ENANTIOSELECTIVE REARRANGEMENT OF A MESO-EPOXIDE TO AN ALLYL ALCOHOL FOR CARBOCYCLIC NUCLEOSIDE SYNTHESIS - AN INTERNAL ALKOXIDE EFFECT

被引：29

作者：

HODGSON, DM ^{[1
]}

WITHERINGTON, J ^{[1
]}

MOLONEY, BA ^{[1
]}

机构：

[1] SCHERING AGROCHEM LTD,WALDEN CB10 1XL,ESSEX,ENGLAND

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 03期

关键词：

D O I：

10.1016/S0957-4166(00)86200-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis of the enantiomeric cis-4-(hydroxymethyl)cyclopent-2-ene-1-ols 2 and 3 (R = H) via a highly enantioselective rearrangement of cis-6-oxabicyclo[3.1.0]hexane-3-methanol 4 (R = H) using the dilithium salts of (+)- or (-)-norephedrine is described.

引用

页码：337 / 338

页数：2

共 13 条

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