Synthesis of optically active diols using an efficient polymer bound cinchona alkaloid derivative

被引：30

作者：

Petri, A ^{[1
]}

Pini, D ^{[1
]}

Rapaccini, S ^{[1
]}

Salvadori, P ^{[1
]}

机构：

[1] UNIV PISA,DIPARTIMENTO CHIM & CHIM IND,CNR,CTR STUDIO MACROMOLEC STEREORDINATE & OTTICAMENTE,I-56126 PISA,ITALY

来源：

CHIRALITY | 1995年 / 7卷 / 08期

关键词：

asymmetric dihydroxylation; enantiomeric excesses; polymerization; chiral separation; optically active diols;

D O I：

10.1002/chir.530070805

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new insoluble polymer containing a Cinchona alkaloid derivative has been synthesized and used as chiral ligand in the heterogeneous enantioselective dihydroxylation of olefins. It is shown that the enantioselectivity of the optically active diols obtained from both aliphatic and aromatic substrates is always comparable to that observed in the homogeneous phase under the same reaction conditions. A method for evaluating the enantiomeric excesses of the optically active products is also described. (C) 1995 Wiley-Liss, Inc.

引用

页码：580 / 585

页数：6

共 17 条

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