DIRECT SYNTHESIS OF 2,4-DIAMINOQUINAZOLINES FROM 2-FLUOROBENZONITRILES

[1] Armarego W. M. F., 1967, FUSED PYRIMIDINES 1

[2] SYNTHESIS OF 5-SUBSTITUTED QUINAZOLINES AS POTENTIAL ANTIMALARIAL AGENTS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (11) : 1233 - 1237

[3] ANTIMALARIAL DRUGS .24. FOLATE ANTAGONISTS .2. 2,4-DIAMINO-6-[[ARALKYL AND (HETEROCYCLIC)METHYL]AMINO]QUINAZOLINES, A NOVEL CLASS OF ANTIMETABOLITES OF INTEREST IN DRUG-RESISTANT MALARIA AND CHAGAS-DISEASE [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (08) : 812 - &

[4] QUINAZOLINE ANALOGUES OF FOLIC ACID [J]. JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1970, (08): : 997 - &

[5] POTENTIAL ANTILEPROTIC AGENTS .3. INHIBITION OF MYCOBACTERIAL DIHYDROFOLIC REDUCTASE BY 2,4-DIAMINO-5-METHYL-6-ALKYLQUINAZOLINES [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (07) : 762 - 764

[6] FOLATE ANTAGONISTS .13. 2,4-DIAMINO-6-[ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL)THIO]QUINAZOLINE AND RELATED 2,4-DIAMINO-6-[(PHENYL- AND NAPHTHYL)THIO]QUINAZOLINES, A UNIQUE CLASS OF ANTI-METABOLITES WITH EXTRAORDINARY ANTI-MALARIAL AND ANTIBACTERIAL EFFECTS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (10) : 1059 - 1070

[7] FOLATE ANTAGONISTS .20. SYNTHESIS AND ANTI-TUMOR AND ANTI-MALARIAL PROPERTIES OF TRIMETREXATE AND RELATED 6-[(PHENYLAMINO)METHYL]-2,4-QUINAZOLINEDIAMINES [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (12) : 1753 - 1760

[8] GUPTON JT, 1982, SYNTH COMMUN, V12, P907

[9] HUTCHISON DJ, 1971, ANN NY ACAD SCI, V186, P496

[10] IDOUX JP, 1983, J ORG CHEM, V48, P3371

[1] Armarego W. M. F., 1967, FUSED PYRIMIDINES 1

[2] SYNTHESIS OF 5-SUBSTITUTED QUINAZOLINES AS POTENTIAL ANTIMALARIAL AGENTS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (11) : 1233 - 1237

[3] ANTIMALARIAL DRUGS .24. FOLATE ANTAGONISTS .2. 2,4-DIAMINO-6-[[ARALKYL AND (HETEROCYCLIC)METHYL]AMINO]QUINAZOLINES, A NOVEL CLASS OF ANTIMETABOLITES OF INTEREST IN DRUG-RESISTANT MALARIA AND CHAGAS-DISEASE [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (08) : 812 - &

[4] QUINAZOLINE ANALOGUES OF FOLIC ACID [J]. JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1970, (08): : 997 - &

[5] POTENTIAL ANTILEPROTIC AGENTS .3. INHIBITION OF MYCOBACTERIAL DIHYDROFOLIC REDUCTASE BY 2,4-DIAMINO-5-METHYL-6-ALKYLQUINAZOLINES [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (07) : 762 - 764

[6] FOLATE ANTAGONISTS .13. 2,4-DIAMINO-6-[ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL)THIO]QUINAZOLINE AND RELATED 2,4-DIAMINO-6-[(PHENYL- AND NAPHTHYL)THIO]QUINAZOLINES, A UNIQUE CLASS OF ANTI-METABOLITES WITH EXTRAORDINARY ANTI-MALARIAL AND ANTIBACTERIAL EFFECTS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (10) : 1059 - 1070

[7] FOLATE ANTAGONISTS .20. SYNTHESIS AND ANTI-TUMOR AND ANTI-MALARIAL PROPERTIES OF TRIMETREXATE AND RELATED 6-[(PHENYLAMINO)METHYL]-2,4-QUINAZOLINEDIAMINES [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (12) : 1753 - 1760

[8] GUPTON JT, 1982, SYNTH COMMUN, V12, P907

[9] HUTCHISON DJ, 1971, ANN NY ACAD SCI, V186, P496

[10] IDOUX JP, 1983, J ORG CHEM, V48, P3371