FLUORESCENCE INSITU HYBRIDIZATION - APPLICATIONS IN CYTOGENETICS AND GENE-MAPPING

被引：366

作者：

TRASK, BJ

机构：

[1] B.J. Trask is in the Biomedical Sciences Division, Lawrence Livermore National Laboratory, Livermore

来源：

TRENDS IN GENETICS | 1991年 / 7卷 / 05期

关键词：

D O I：

10.1016/0168-9525(91)90378-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Unique sequences, chromosomal subregions, or entire genomes can be specifically highlighted in metaphase or interphase cells by fluorescence in situ hybridization (FISH). This technique can be used to identify chromosomes, detect chromosomal abnormalities or determine the chromosomal location of specific sequences. FISH plays an increasingly important role in a variety of research areas, including cytogenetics, prenatal diagnosis, tumor biology, gene amplification and gene mapping.

引用

页码：149 / 154

页数：6

共 41 条

[31] DETECTION OF BCR-ABL FUSION IN CHRONIC MYELOGENEOUS LEUKEMIA BY INSITU HYBRIDIZATION
TKACHUK, DC
WESTBROOK, CA
ANDREEFF, M
DONLON, TA
CLEARY, ML
SURYANARAYAN, K
HOMGE, M
REDNER, A
GRAY, J
PINKEL, D
[J]. SCIENCE, 1990, 250 (4980) : 559 - 562
[32] FLUORESCENCE INSITU HYBRIDIZATION TO INTERPHASE CELL-NUCLEI IN SUSPENSION ALLOWS FLOW CYTOMETRIC ANALYSIS OF CHROMOSOME CONTENT AND MICROSCOPIC ANALYSIS OF NUCLEAR-ORGANIZATION
TRASK, B
VANDENENGH, G
PINKEL, D
MULLIKIN, J
WALDMAN, J
VANDEKKEN, H
GRAY, J
[J]. HUMAN GENETICS, 1988, 78 (03) : 251 - 259
[33] TRASK B, 1989, AM J HUM GENET, V45, P739
[34] THE PROXIMITY OF DNA-SEQUENCES IN INTERPHASE CELL-NUCLEI IS CORRELATED TO GENOMIC DISTANCE AND PERMITS ORDERING OF COSMIDS SPANNING 250 KILOBASE PAIRS
TRASK, B
PINKEL, D
VANDENENGH, G
[J]. GENOMICS, 1989, 5 (04) : 710 - 717
[35] EARLY DIHYDROFOLATE-REDUCTASE GENE AMPLIFICATION EVENTS IN CHO CELLS USUALLY OCCUR ON THE SAME CHROMOSOME ARM AS THE ORIGINAL LOCUS
TRASK, BJ
HAMLIN, JL
[J]. GENES & DEVELOPMENT, 1989, 3 (12A) : 1913 - 1925
[36] TRASK BJ, 1991, AM J HUM GENET, V48, P1
[37] SIMULTANEOUS IDENTIFICATION AND BANDING OF HUMAN-CHROMOSOME MATERIAL IN SOMATIC-CELL HYBRIDS
TUCKER, JD
CHRISTENSEN, ML
CARRANO, AV
[J]. CYTOGENETICS AND CELL GENETICS, 1988, 48 (02): : 103 - 106
[38] MAPPING OF SINGLE-COPY DNA-SEQUENCES ON HUMAN-CHROMOSOMES BY INSITU HYBRIDIZATION WITH BIOTINYLATED PROBES - ENHANCEMENT OF DETECTION SENSITIVITY BY INTENSIFIED-FLUORESCENCE DIGITAL-IMAGING MICROSCOPY
VIEGASPEQUIGNOT, E
DUTRILLAUX, B
MAGDELENAT, H
COPPEYMOISAN, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (02) : 582 - 586
[39] VOGT P, 1990, HUM GENET, V84, P301
[40] WADA M, 1990, AM J HUM GENET, V46, P95

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