MICROBIAL ADHESINS RECOGNIZING EXTRACELLULAR-MATRIX MACROMOLECULES

被引：189

作者：

PATTI, JM

HOOK, M

机构：

[1] Institute of Biosciences and Technology, Center for Extracellular Matrix Biology, Texas A and M University, Houston, TX 771131

来源：

CURRENT OPINION IN CELL BIOLOGY | 1994年 / 6卷 / 05期

关键词：

D O I：

10.1016/0955-0674(94)90104-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Microorganisms express a family of cell-surface adhesins that specifically recognize and bind components of the extracellular matrix. Adhesion of microorganisms to host tissues represents a critical phase in the development of many types of infections. Recent studies have focused on the mechanisms of microbial attachment at a molecular level, including the identification of ligand-binding domains in several cell-surface adhesins from Gram-positive bacteria and the construction of adhesin-deficient isogenic mutants.

引用

页码：752 / 758

页数：7

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