SOLID-PHASE N-GLYCOPEPTIDE SYNTHESIS USING ALLYL SIDE-CHAIN PROTECTED FMOC-AMINO ACIDS

被引：31

作者：

KATES, SA

DELATORRE, BG

ERITJA, R

ALBERICIO, F

机构：

[1] MILLIPORE CORP,BEDFORD,MA 01730

[2] CSIC,CID,E-08034 BARCELONA,SPAIN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 07期

关键词：

GLYCOPEPTIDES; ALLYL ESTERS; ORTHOGONAL PROTECTION; SOLID-PHASE SYNTHESIS;

D O I：

10.1016/S0040-4039(00)79958-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for the preparation of glycopeptides using a three-dimensional orthogonal solid-phase strategy (Fmoc/tBu/allyl) with selective allyl removal and direct coupling of glycosylamines to the carboxyl function while the peptide is attached to the resin is described.

引用

页码：1033 / 1034

页数：2

共 16 条

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