SPECIFIC METAPHASE AND INTERPHASE DETECTION OF THE BREAKPOINT REGION IN 8Q24 OF BURKITT-LYMPHOMA CELLS BY TRIPLE-COLOR FLUORESCENCE INSITU HYBRIDIZATION

被引：85

作者：

RIED, T

LENGAUER, C

CREMER, T

WIEGANT, J

RAAP, AK

VANDERPLOEG, M

GROITL, P

LIPP, M

机构：

[1] UNIV HEIDELBERG,INST HUMAN GENET & ANTHROPOL,NEUENHEIMER FELD 328,W-6900 HEIDELBERG,GERMANY

[2] LEIDEN UNIV,FAC MED,DEPT CYTOCHEM & CYTOMETRY,2300 RA LEIDEN,NETHERLANDS

[3] UNIV MUNICH,INST BIOCHEM,W-8000 MUNICH 2,GERMANY

来源：

GENES CHROMOSOMES & CANCER | 1992年 / 4卷 / 01期

关键词：

D O I：

10.1002/gcc.2870040109

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8 in combination with bacteriophage clones flanking the breakpoint in 8q24 of the Burkitt lymphoma cell line JI was used for the specific delineation of this breakpoint in individual tumor cells. With this approach, tumor-specific breakpoints in translocation chromosomes can be detected at all stages of the cell cycle with high specificity.

引用

页码：69 / 74

页数：6

共 34 条

[1] ANASTASI J, 1990, AM J PATHOL, V136, P131
[2] DETECTION OF THE PHILADELPHIA-CHROMOSOME IN INTERPHASE NUCLEI
ARNOLDUS, EPJ
WIEGANT, J
NOORDERMEER, IA
WESSELS, JW
BEVERSTOCK, GC
GROSVELD, GC
VANDERPLOEG, M
RAAP, AK
[J]. CYTOGENETICS AND CELL GENETICS, 1990, 54 (3-4): : 108 - &
[3] INSITU HYBRIDIZATION BANDING OF HUMAN-CHROMOSOMES WITH ALU-PCR PRODUCTS - A SIMULTANEOUS KARYOTYPE FOR GENE-MAPPING STUDIES
BALDINI, A
WARD, DC
[J]. GENOMICS, 1991, 9 (04) : 770 - 774
[4] EPSTEIN-BARR VIRUS-POSITIVE BURKITTS-LYMPHOMA IN A GERMAN WOMAN DURING PREGNANCY
BORNKAMM, GW
KADUK, B
KACHEL, G
SCHNEIDER, U
FRESEN, KO
SCHWANITZ, G
HERMANEK, P
[J]. BLUT, 1980, 40 (03): : 167 - 177
[5] RAPID INTERPHASE AND METAPHASE ASSESSMENT OF SPECIFIC CHROMOSOMAL CHANGES IN NEUROECTODERMAL TUMOR-CELLS BY INSITU HYBRIDIZATION WITH CHEMICALLY MODIFIED DNA PROBES
CREMER, T
TESIN, D
HOPMAN, AHN
MANUELIDIS, L
[J]. EXPERIMENTAL CELL RESEARCH, 1988, 176 (02) : 199 - 220
[6] DETECTION OF CHROMOSOME-ABERRATIONS IN THE HUMAN INTERPHASE NUCLEUS BY VISUALIZATION OF SPECIFIC TARGET DNAS WITH RADIOACTIVE AND NONRADIOACTIVE INSITU HYBRIDIZATION TECHNIQUES - DIAGNOSIS OF TRISOMY-18 WITH PROBE L1.84
CREMER, T
LANDEGENT, J
BRUCKNER, A
SCHOLL, HP
SCHARDIN, M
HAGER, HD
DEVILEE, P
PEARSON, P
VANDERPLOEG, M
[J]. HUMAN GENETICS, 1986, 74 (04) : 346 - 352
[7] DETECTION OF CHROMOSOME-ABERRATIONS IN METAPHASE AND INTERPHASE TUMOR-CELLS BY INSITU HYBRIDIZATION USING CHROMOSOME-SPECIFIC LIBRARY PROBES
CREMER, T
LICHTER, P
BORDEN, J
WARD, DC
MANUELIDIS, L
[J]. HUMAN GENETICS, 1988, 80 (03) : 235 - 246
[8] CREMER T, 1991, REV EUR TECHNOL BIOM, V13, P50
[9] THERMOSTABLE DNA-POLYMERASE CHAIN AMPLIFICATION OF T(14-18) CHROMOSOME BREAKPOINTS AND DETECTION OF MINIMAL RESIDUAL DISEASE
CRESCENZI, M
SETO, M
HERZIG, GP
WEISS, PD
GRIFFITH, RC
KORSMEYER, SJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (13) : 4869 - 4873
[10] DEVILEE P, 1988, CANCER RES, V48, P5825

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