EVIDENCE THAT NEUROFIBRILLARY TANGLES UNDERGO GLIAL MODIFICATION

被引：23

作者：

IKEDA, K

AKIYAMA, H

HAGA, C

HAGA, S

机构：

[1] Tokyo Institute of Psychiatry (previous Psychiatric Research Institute of Tokyo), Department of Neuropathology, Tokyo, 156, 2-1-8, Kamikitazawa, Setagaya-ku

[2] Tokyo Institute of Psychiatry (previous Psychiatric Research Institute of Tokyo), Department of Ultrastructure, Tokyo, 156, 2-1-8, Kamikitazawa, Setagaya-ku

来源：

ACTA NEUROPATHOLOGICA | 1992年 / 85卷 / 01期

关键词：

ALZHEIMER-TYPE DEMENTIA; GHOST TANGLE; MICROGLIA; ASTROCYTE;

D O I：

10.1007/BF00304639

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Ghost tangles, neurofibrillary tangles (NFTs) emerging into extracellular space, appear to be subjected to some microglial association in addition to an invasion of astrocytic processes. Our findings lead us to speculate that the NFTs undergo structural and immunocytochemical modification. Electron microscopic observation of the NFTs in the vascular region indicated either the discharge of NFTs into the vessel or formation of NFTs in the astrocytic end-foot.

引用

页码：101 / 104

页数：4

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