STEREOSELECTIVE SYNTHESIS OF TETRAHYDROFURANS AND TETRAHYDROPYRANS BY NI(0) PROMOTED TANDEM CYCLIZATION-CARBONYLATION

被引：7

作者：

DELGADO, A ^{[1
]}

LLEBARIA, A ^{[1
]}

CAMPS, F ^{[1
]}

MORETO, JM ^{[1
]}

机构：

[1] CSIC,CID,DEPT QUIM ORGAN BIOL,E-08034 BARCELONA,SPAIN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(00)76727-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of different vinyl bromides (1a-3a), beating phenyl substituted alkenyloxyalkyl groups, with Ni(CO)4 affords the corresponding substituted cyclic ethers 1b-3b in moderate to good yields and high diastereoselectivity. In the cyclization of 1a, the stereoselectivity of the process can be reversed by the use of additives, such as KOAc, TIOAc, Cs2CO3, and KOCOCF3.

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收藏

页码：4011 / 4014

页数：4

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