IMMUNOLOGICALLY IGNORANT AUTOREACTIVE T-CELLS, EPITOPE SPREADING AND REPERTOIRE LIMITATION

被引：127

作者：

ELSON, CJ

BARKER, RN

THOMPSON, SJ

WILLIAMS, NA

机构：

来源：

IMMUNOLOGY TODAY | 1995年 / 16卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0167-5699(95)80091-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The factors that may cause antigen-presenting cells to alter the pattern of protein Processing and presentation to autoreactive T cells, and thereby stimulate autoimmune disease, are currently under debate. In this article, Chris Elson and colleagues suggest that cytokines associated with T helper 1 (Th1) cells alter the processing of proteins and that this effect can be counteracted by Th2-associated cytokines.

引用

页码：71 / 76

页数：6

共 40 条

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