COEXPRESSION OF GABA(A) RECEPTOR GAMMA-1 AND GAMMA-2 SUBUNITS IN THE RAT TRIGEMINAL GANGLION

被引：23

作者：

KONDO, E

KIYAMA, H

ARAKI, T

SHIDA, T

UEDA, Y

TOHYAMA, M

机构：

[1] OSAKA UNIV,SCH MED,DEPT NEUROANAT,SUITA,OSAKA 565,JAPAN

[2] OSAKA DENT UNIV,DEPT ANESTHESIOL,CHUO KU,OSAKA,OSAKA 540,JAPAN

来源：

MOLECULAR BRAIN RESEARCH | 1994年 / 21卷 / 3-4期

关键词：

GABA; GABA(A) RECEPTOR; GAMMA-1; SUBUNIT; GAMMA-2; COEXPRESSION; TRIGEMINAL GANGLION; PRIMARY AFFERENT SYSTEM;

D O I：

10.1016/0169-328X(94)90269-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

We examined the expression of gamma-aminobutyric acid (GABA)(A) receptor gamma 1 and gamma 2 subunit mRNAs in the rat trigeminal ganglion using in situ hybridization histochemistry. Most ganglion cells expressed both gamma 1 and gamma 2 mRNAs simultaneously. These findings are a marked contrast to. the findings in the central nervous system where areas expressing both subunits are rare. In addition, we demonstrated using immunohistochemistry that the gamma 1 subunit is also expressed at the protein level in trigeminal ganglion neurons and fibers in the trigeminal spinal nucleus.

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收藏

页码：363 / 367

页数：5

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