DIASTEREOSELECTIVE SYNTHESIS OF THE POTENT ANTIVIRAL AGENT (-)-2'-DEOXY-3'-THIACYTIDINE AND ITS ENANTIOMER

被引：53

作者：

JIN, HL ^{[1
]}

SIDDIQUI, MA ^{[1
]}

EVANS, CA ^{[1
]}

TSE, HLA ^{[1
]}

MANSOUR, TS ^{[1
]}

GOODYEAR, MD ^{[1
]}

RAVENSCROFT, P ^{[1
]}

BEELS, CD ^{[1
]}

机构：

[1] GLAXO RES & DEV LTD,WARE SG12 0DJ,HERTS,ENGLAND

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 08期

关键词：

D O I：

10.1021/jo00113a050

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：2621 / 2623

页数：3

共 17 条

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[3] INSITU COMPLEXATION DIRECTS THE STEREOCHEMISTRY OF N-GLYCOSYLATION IN THE SYNTHESIS OF OXATHIOLANYL AND DIOXOLANYL NUCLEOSIDE ANALOGS
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[4] SYNTHESIS, ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS, AND ANTI-HEPATITIS-B VIRUS ACTIVITY OF PYRIMIDINE OXATHIOLANE NUCLEOSIDES
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[5] CHU C K, 1991, Journal of Organic Chemistry, V56, P6503, DOI 10.1021/jo00023a010
[6] (-)-2'-DEOXY-3'-THIACYTIDINE IS A POTENT, HIGHLY SELECTIVE INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 AND TYPE-2 REPLICATION INVITRO
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[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1992, 36 (04) : 733 - 739
[7] THE SEPARATED ENANTIOMERS OF 2'-DEOXY-3'-THIACYTIDINE (BCH-189) BOTH INHIBIT HUMAN-IMMUNODEFICIENCY-VIRUS REPLICATION INVITRO
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[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1992, 36 (01) : 202 - 205
[8] DIENSTAG JL, 1994, 2ND ANN ANT GEN APPR
[9] INHIBITION OF THE REPLICATION OF HEPATITIS-B VIRUS INVITRO BY 2',3'-DIDEOXY-3'-THIACYTIDINE AND RELATED ANALOGS
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (19) : 8495 - 8499
[10] ENZYME-MEDIATED ENANTIOSELECTIVE PREPARATION OF PURE ENANTIOMERS OF THE ANTIVIRAL AGENT 2',3'-DIDEOXY-5-FLUORO-3'-THIACYTIDINE (FTC) AND RELATED-COMPOUNDS
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[J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (21) : 5563 - 5565

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