A PRACTICAL SYNTHESIS OF 2-BUTYL-4(5)-CHLORO-5(4)-HYDROXYMETHYL-1H-IMIDAZOLE

被引：12

作者：

SHI, YJ

FREY, LF

TSCHAEN, DM

VERHOEVEN, TR

机构：

[1] Department of Process Research Merck Research Laboratory, Rahway, New Jersey 07065

来源：

SYNTHETIC COMMUNICATIONS | 1993年 / 23卷 / 18期

关键词：

D O I：

10.1080/00397919308012598

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical process for the synthesis of 2-butyl-4-hydroxymethyl imidazole (4) followed by chlorination to provide chloroimidazole 1 in an overall 71% yield has been developed.

引用

页码：2623 / 2630

页数：8