Sex and Gender Differences in Non-Small Cell Lung Cancer

被引：63

作者：

Donington, Jessica S. ^{[1
]}

Colson, Yolonda L. ^{[2
]}

机构：

[1] NYU, Sch Med, Dept Cardiothorac Surg, 530 1st Ave,Suite 9V, New York, NY 10016 USA

[2] Harvard Med Sch, Brigham & Womens Hosp, Div Thorac Surg, Womens Lung Canc Program, Boston, MA USA

来源：

SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY | 2011年 / 23卷 / 02期

关键词：

non-small cell lung carcinoma; gender; epidemiology; prognosis; tobacco; estrogen;

D O I：

10.1053/j.semtcvs.2011.07.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Historically, lung cancer has been viewed as a male disease, but during the past 50 years there has been a dramatic increase in the incidence of lung cancer in women. Lung cancer is currently the most common cause of cancer death in American women, accounting for more than one quarter of all cancer deaths. This has been attributed to a significant increase in tobacco consumption by women; however, approximately 1 in 5 women with lung cancer never smoked. As the incidence of lung cancer in women has increased, significant gender-based differences in epidemiology, biology, and treatment responses have become evident and warrant further investigation to advance the treatment of lung cancer in all patients. © 2011 Elsevier Inc.

引用

页码：137 / 145

页数：9

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