NORMAL AND ABNORMAL BIOLOGY OF THE BETA-AMYLOID PRECURSOR PROTEIN

被引：616

作者：

SELKOE, DJ

机构：

[1] HARVARD UNIV,SCH MED,NEUROSCI PROGRAM,BOSTON,MA 02115

[2] BRIGHAM & WOMENS HOSP,CTR NEUROL DIS,BOSTON,MA 02115

来源：

ANNUAL REVIEW OF NEUROSCIENCE | 1994年 / 17卷

关键词：

ALZHEIMERS DISEASE; NEURODEGENERATION; AMYLOID BETA-PROTEIN; TRANSMEMBRANE PROTEINS; AMYLOIDOSIS;

D O I：

10.1146/annurev.neuro.17.1.489

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：489 / 517

页数：29

共 138 条

[31] SEGREGATION OF A MISSENSE MUTATION IN THE AMYLOID PRECURSOR PROTEIN GENE WITH FAMILIAL ALZHEIMERS-DISEASE [J].

GOATE, A ;

CHARTIERHARLIN, MC ;

MULLAN, M ;

BROWN, J ;

CRAWFORD, F ;

FIDANI, L ;

GIUFFRA, L ;

HAYNES, A ;

IRVING, N ;

JAMES, L ;

MANT, R ;

NEWTON, P ;

ROOKE, K ;

ROQUES, P ;

TALBOT, C ;

PERICAKVANCE, M ;

ROSES, A ;

WILLIAMSON, R ;

ROSSOR, M ;

OWEN, M ;

HARDY, J .

NATURE, 1991, 349 (6311) :704-706

[32] PROCESSING OF THE AMYLOID PROTEIN-PRECURSOR TO POTENTIALLY AMYLOIDOGENIC DERIVATIVES [J].

GOLDE, TE ;

ESTUS, S ;

YOUNKIN, LH ;

SELKOE, DJ ;

YOUNKIN, SG .

SCIENCE, 1992, 255 (5045) :728-730

[33] CHARACTERIZATION AND CHROMOSOMAL LOCALIZATION OF A CDNA-ENCODING BRAIN AMYLOID OF ALZHEIMERS-DISEASE [J].

GOLDGABER, D ;

LERMAN, MI ;

MCBRIDE, OW ;

SAFFIOTTI, U ;

GAJDUSEK, DC .

SCIENCE, 1987, 235 (4791) :877-880

[34] ISOLATION AND PARTIAL CHARACTERIZATION OF NEUROFIBRILLARY TANGLES AND AMYLOID PLAQUE CORE IN ALZHEIMERS-DISEASE - IMMUNOHISTOLOGICAL STUDIES [J].

GOREVIC, PD ;

GONI, F ;

PONSESTEL, B ;

ALVAREZ, F ;

PERESS, NS ;

FRANGIONE, B .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1986, 45 (06) :647-664

[35]

GRIFFIN WST, 1989, P NATL ACAD SCI USA, V86, P7611

[36] AMYLOID BETA-PEPTIDE IS PRODUCED BY CULTURED-CELLS DURING NORMAL METABOLISM [J].

HAASS, C ;

SCHLOSSMACHER, MG ;

HUNG, AY ;

VIGOPELFREY, C ;

MELLON, A ;

OSTASZEWSKI, BL ;

LIEBERBURG, I ;

KOO, EH ;

SCHENK, D ;

TEPLOW, DB ;

SELKOE, DJ .

NATURE, 1992, 359 (6393) :322-325

[37]

HAASS C, 1993, J BIOL CHEM, V268, P3021

[38]

HAASS C, 1991, J NEUROSCI, V11, P3783

[39] TARGETING OF CELL-SURFACE BETA-AMYLOID PRECURSOR PROTEIN TO LYSOSOMES - ALTERNATIVE PROCESSING INTO AMYLOID-BEARING FRAGMENTS [J].

HAASS, C ;

KOO, EH ;

MELLON, A ;

HUNG, AY ;

SELKOE, DJ .

NATURE, 1992, 357 (6378) :500-503

[40] FRAMING BETA-AMYLOID [J].

HARDY, J .

NATURE GENETICS, 1992, 1 (04) :233-234

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