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NORMAL AND ABNORMAL BIOLOGY OF THE BETA-AMYLOID PRECURSOR PROTEIN

被引：616
作者：
SELKOE, DJ
机构：
[1] HARVARD UNIV,SCH MED,NEUROSCI PROGRAM,BOSTON,MA 02115
[2] BRIGHAM & WOMENS HOSP,CTR NEUROL DIS,BOSTON,MA 02115
来源：
ANNUAL REVIEW OF NEUROSCIENCE | 1994年 / 17卷
关键词：
ALZHEIMERS DISEASE; NEURODEGENERATION; AMYLOID BETA-PROTEIN; TRANSMEMBRANE PROTEINS; AMYLOIDOSIS;
D O I：
10.1146/annurev.neuro.17.1.489
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
引用
收藏
页码：489 / 517
页数：29
相关论文
共 138 条
[11]  
BUXBAUM JD, 1992, P NATL ACAD SCI USA, V89, P3055
[12]   RELEASE OF EXCESS AMYLOID BETA-PROTEIN FROM A MUTANT AMYLOID BETA-PROTEIN PRECURSOR [J].
CAI, XD ;
GOLDE, TE ;
YOUNKIN, SG .
SCIENCE, 1993, 259 (5094) :514-516
[13]   PROTEIN-PHOSPHORYLATION REGULATES SECRETION OF ALZHEIMER-BETA-A4 AMYLOID PRECURSOR PROTEIN [J].
CAPORASO, GL ;
GANDY, SE ;
BUXBAUM, JD ;
RAMABHADRAN, TV ;
GREENGARD, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (07) :3055-3059
[14]   ENZYMATICALLY ACTIVE LYSOSOMAL PROTEASES ARE ASSOCIATED WITH AMYLOID DEPOSITS IN ALZHEIMER BRAIN [J].
CATALDO, AM ;
NIXON, RA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (10) :3861-3865
[15]   AN ANTIBODY TO BETA-AMYLOID AND THE AMYLOID PRECURSOR PROTEIN INHIBITS CELL-SUBSTRATUM ADHESION IN MANY MAMMALIAN-CELL TYPES [J].
CHEN, M ;
YANKNER, BA .
NEUROSCIENCE LETTERS, 1991, 125 (02) :223-226
[16]  
CHEN WJ, 1990, J BIOL CHEM, V265, P3116
[17]   MUTATION OF THE BETA-AMYLOID PRECURSOR PROTEIN IN FAMILIAL ALZHEIMERS-DISEASE INCREASES BETA-PROTEIN PRODUCTION [J].
CITRON, M ;
OLTERSDORF, T ;
HAASS, C ;
MCCONLOGUE, L ;
HUNG, AY ;
SEUBERT, P ;
VIGOPELFREY, C ;
LIEBERBURG, I ;
SELKOE, DJ .
NATURE, 1992, 360 (6405) :672-674
[18]  
COCHRAN E, 1991, AM J PATHOL, V139, P485
[19]   EVIDENCE FOR LYSOSOMAL PROCESSING OF AMYLOID BETA-PROTEIN PRECURSOR IN CULTURED-CELLS [J].
COLE, GM ;
HUYNH, TV ;
SAITOH, T .
NEUROCHEMICAL RESEARCH, 1989, 14 (10) :933-939
[20]   SENILE PLAQUE NEURITES IN ALZHEIMER-DISEASE ACCUMULATE AMYLOID PRECURSOR PROTEIN [J].
CRAS, P ;
KAWAI, M ;
LOWERY, D ;
GONZALEZDEWHITT, P ;
GREENBERG, B ;
PERRY, G .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (17) :7552-7556
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