PREPARATION OF OLIGONUCLEOTIDE-DEXAMETHASONE CONJUGATES

被引：15

作者：

ACEDO, M

TARRASON, G

PIULATS, J

MANN, M

WILM, M

ERITJA, R

机构：

[1] CSIC,CID,DEPT MOLEC GENET,E-08034 BARCELONA,SPAIN

[2] MERCK FARMA & QUIM,BIOINVEST LAB,E-08010 BARCELONA,SPAIN

[3] EUROPEAN MOLEC BIOL LAB,D-69012 HEIDELBERG,GERMANY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 15期

关键词：

D O I：

10.1016/0960-894X(95)00274-W

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Oligonucleotides carrying a dexamethasone molecule at the 5'-end have been prepared. During the preparation of these conjugates an intramolecular side reaction was detected and minimized.

引用

页码：1577 / 1580

页数：4

共 17 条

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