学术探索
学术期刊
新闻热点
数据分析
智能评审

DEGLYCO GABA,GLY-DESACETAMIDOBLEOMYCIN-A2 - A SIMPLIFIED SYNTHETIC MODEL FOR BLEOMYCIN-A2

被引：33
作者：
BOGER, DL
MENEZES, RF
DANG, Q
YANG, WJ
机构：
[1] Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1992年 / 2卷 / 03期
关键词：
D O I：
10.1016/S0960-894X(01)81076-3
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The synthesis of 2, a simplified synthetic model for bleomycin A2, and the pre
引用
收藏
页码：261 / 266
页数：6
相关论文
共 59 条
  • [31] MAN-DESIGNED BLEOMYCIN WITH ALTERED SEQUENCE SPECIFICITY IN DNA CLEAVAGE
    OTSUKA, M
    MASUDA, T
    HAUPT, A
    OHNO, M
    SHIRAKI, T
    SUGIURA, Y
    MAEDA, K
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (02) : 838 - 845
  • [32] SYNTHETIC STUDIES ON AN ANTITUMOR ANTIBIOTIC BLEOMYCIN .25. AN EFFICIENT SYNTHESIS OF ERYTHRO-BETA-HYDROXY-L-HISTIDINE, THE PIVOTAL AMINO-ACID OF BLEOMYCIN-FE(II)-O2 COMPLEX
    OWA, T
    OTSUKA, M
    OHNO, M
    [J]. CHEMISTRY LETTERS, 1988, (11) : 1873 - 1874
  • [33] Povirk L.F., 1983, MOL ASPECTS ANTICANC
  • [34] BINDING OF BLEOMYCIN TO DNA - INTERCALATION OF THE BITHIAZOLE RINGS
    POVIRK, LF
    HOGAN, M
    DATTAGUPTA, N
    [J]. BIOCHEMISTRY, 1979, 18 (01) : 96 - 101
  • [35] COPPER(II).BLEOMYCIN, IRON(III).BLEOMYCIN, AND COPPER(II).PHLEOMYCIN - COMPARATIVE-STUDY OF DEOXYRIBONUCLEIC-ACID BINDING
    POVIRK, LF
    HOGAN, M
    DATTAGUPTA, N
    BUECHNER, M
    [J]. BIOCHEMISTRY, 1981, 20 (03) : 665 - 670
  • [36] AN IMPROVED TOTAL SYNTHESIS OF BLEOMYCIN
    SAITO, S
    UMEZAWA, Y
    YOSHIOKA, T
    TAKITA, T
    UMEZAWA, H
    MURAOKA, Y
    [J]. JOURNAL OF ANTIBIOTICS, 1983, 36 (01) : 92 - 95
  • [37] A NEW SYNTHESIS OF DEGLYCO-BLEOMYCIN-A2 AIMING AT THE TOTAL SYNTHESIS OF BLEOMYCIN
    SAITO, SI
    UMEZAWA, Y
    MORISHIMA, H
    TAKITA, T
    UMEZAWA, H
    NARITA, M
    OTSUKA, M
    KOBAYASHI, S
    OHNO, M
    [J]. TETRAHEDRON LETTERS, 1982, 23 (05) : 529 - 532
  • [38] SYNTHESIS AND DNA-BINDING OF [3-[2'(2-ACETAMIDOETHYL)-2,4'-BITHIAZOLE-4-CARBOXAMIDO]PROPYL]DIMETHYLSULFONIUM CHLORIDE, A FRAGMENT OF BLEOMYCIN-A2
    SAKAI, TT
    RIORDAN, JM
    BOOTH, TE
    GLICKSON, JD
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (03) : 279 - 285
  • [39] BLEOMYCIN CONGENERS EXHIBITING ALTERED DNA CLEAVAGE SPECIFICITY
    SHIPLEY, JB
    HECHT, SM
    [J]. CHEMICAL RESEARCH IN TOXICOLOGY, 1988, 1 (01) : 25 - 27
  • [40] MECHANISMS OF BLEOMYCIN-INDUCED DNA-DEGRADATION
    STUBBE, J
    KOZARICH, JW
    [J]. CHEMICAL REVIEWS, 1987, 87 (05) : 1107 - 1136
123456