A NEW SYNTHETIC ROUTE FOR THE GAMMA-LACTONE PRECURSORS OF HYDROXYETHYLENE DIPEPTIDE ISOSTERES

被引：11

作者：

SAKURAI, M ^{[1
]}

HATA, T ^{[1
]}

YABE, Y ^{[1
]}

机构：

[1] SANKYO CO LTD,ANALYT & METAB RES LABS,TOKYO 140,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(00)73819-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Delta-Phthalimido-gamma-ketoesters were obtained by the Pd catalyzed coupling reaction between acid chlorides and organozinc reagents derived from beta-iodoesters, and were converted into the gamma-lactone precursors of Phe-psi[H.E.]-Ala and Phe-psi[H.E.]-Pro (15a,b-18a,b).

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页码：5939 / 5942

页数：4

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