NMR-STUDIES OF DIFFERENCES IN THE CONFORMATIONS AND DYNAMICS OF LIGAND COMPLEXES FORMED WITH MUTANT DIHYDROFOLATE REDUCTASES

被引:27
作者
BIRDSALL, B
ANDREWS, J
OSTLER, G
TENDLER, SJB
FEENEY, J
ROBERTS, GCK
DAVIES, RW
CHEUNG, HTA
机构
[1] ALLELIX BIOPHARMACEUT,MISSISSAUGA,ONTARIO,CANADA
[2] UNIV SYDNEY,DEPT PHARM,SYDNEY,NSW 2006,AUSTRALIA
[3] UNIV LEICESTER,DEPT BIOCHEM,LEICESTER LE1 7RH,ENGLAND
[4] UNIV MANCHESTER,INST SCI & TECHNOL,DEPT BIOCHEM,MANCHESTER M60 1QD,LANCS,ENGLAND
关键词
D O I
10.1021/bi00429a062
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:1353 / 1362
页数:10
相关论文
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