TUMOR LOCATION DETECTED WITH RADIOACTIVELY LABELED MONOCLONAL ANTIBODY AND EXTERNAL SCINTIGRAPHY

被引：160

作者：

BALLOU, B

LEVINE, G

HAKALA, TR

SOLTER, D

机构：

[1] UNIV PITTSBURGH,SCH MED,DEPT PATHOL,PITTSBURGH,PA 15261

[2] UNIV PITTSBURGH,SCH MED,DEPT RADIOL,PITTSBURGH,PA 15261

[3] UNIV PITTSBURGH,PRESBYTERIAN HOSP,DEPT NUCL MED,PITTSBURGH,PA 15213

[4] WISTAR INST ANAT & BIOL,PHILADELPHIA,PA 19104

来源：

SCIENCE | 1979年 / 206卷 / 4420期

关键词：

D O I：

10.1126/science.493985

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Murine teratocarcinomas were located in mice by external gamma-ray scintigraphy with an iodine-125-labeled monoclonal antibody specific to the tumors. The specificity of the method was increased by subtracting the radiation produced by an iodine-125-labeled indifferent monoclonal antibody of the same immunoglobulin class as the tumor-specific antibody. Copyright © 1979 AAAS.

引用

页码：844 / 847

页数：4

共 17 条

[1]

BEIHN RM, 1974, J NUCL MED, V15, P371

[2] RADIONUCLIDE IMAGING OF METASTASES FROM RENAL-CELL CARCINOMA BY I-131-LABELED ANTI-TUMOR ANTIBODY [J].