THC-INDUCED PLACE AND TASTE-AVERSIONS IN LEWIS AND SPRAGUE-DAWLEY RATS

被引：118

作者：

PARKER, LA

GILLIES, T

机构：

来源：

BEHAVIORAL NEUROSCIENCE | 1995年 / 109卷 / 01期

关键词：

D O I：

10.1037/0735-7044.109.1.71

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The hedonic properties of delta-9-tetrahydrocannabinol (THC) were assessed in place and taste conditioning paradigms in both Lewis and Sprague-Dawley rat strains. THC produced place avoidance, taste avoidance, and aversive taste reactivity responses in both strains. The Lewis strain displayed more aversive taste reactions and a stronger taste avoidance when conditioned with lower doses of THC than did the Sprague-Dawley strain of rats. THC is an anomalous drug of abuse that appears to be aversive to rats when assessed by these measures.

引用

页码：71 / 78

页数：8

共 42 条

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