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THC-INDUCED PLACE AND TASTE-AVERSIONS IN LEWIS AND SPRAGUE-DAWLEY RATS

被引：118
作者：
PARKER, LA
GILLIES, T
机构：
来源：
BEHAVIORAL NEUROSCIENCE | 1995年 / 109卷 / 01期
关键词：
D O I：
10.1037/0735-7044.109.1.71
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The hedonic properties of delta-9-tetrahydrocannabinol (THC) were assessed in place and taste conditioning paradigms in both Lewis and Sprague-Dawley rat strains. THC produced place avoidance, taste avoidance, and aversive taste reactivity responses in both strains. The Lewis strain displayed more aversive taste reactions and a stronger taste avoidance when conditioned with lower doses of THC than did the Sprague-Dawley strain of rats. THC is an anomalous drug of abuse that appears to be aversive to rats when assessed by these measures.
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页码：71 / 78
页数：8
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