SYRINGOPEPTINS, NEW PHYTOTOXIC LIPODEPSIPEPTIDES OF PSEUDOMONAS-SYRINGAE PV SYRINGAE

被引：119

作者：

BALLIO, A

BARRA, D

BOSSA, F

COLLINA, A

GRGURINA, I

MARINO, G

MONETI, G

PACI, M

PUCCI, P

SEGRE, A

SIMMACO, M

机构：

[1] UNIV LA SAPIENZA, CNR, CTR BIOL MOLEC, I-00185 ROME, ITALY

[2] CNR, IST STRUTTURIST G GIACOMELLO, I-00016 MONTEROTONDO, ITALY

[3] UNIV FEDERICO II, DIPARTIMENTO CHIM ORGAN & BIOL, I-80134 NAPLES, ITALY

[4] UNIV FLORENCE, DIPARTMENTO FARMACOL, CTR SPETTROMETRIA MASSA, I-50134 FLORENCE, ITALY

[5] UNIV TOR VERGATA, DIPARTIMENTO SCI & TECNOL CHIM, I-00173 ROME, ITALY

来源：

FEBS LETTERS | 1991年 / 291卷 / 01期

关键词：

PHYTOTOXIN; LIPODEPSIPEPTIDE; SYRINGOPEPTIN; PSEUDOMONAS-SYRINGAE PV SYRINGAE;

D O I：

10.1016/0014-5793(91)81115-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The primary structure of some new lipodepsipeptides named syringopeptins, produced by plant pathogenic strains of Pseudomonas syringae pv. syringae has been determined by a combination of chemical methods, H-1 and C-13 NMR spectroscopy and FAB mass spectrometry. Two syringomycin-producing strains afforded 3-hydroxydecanoyl-Dhb-Pro-Val-Val-Ala-Ala-Val-Val-Dhb-Ala-Val-Ala-Ala-Dhb-aThr -Ser-Ala-Dhb-Ala-Dab-Dab-Tyr, with Tyr acylating aThr to form a macrolactone ring, and smaller amounts of the 3-hydroxydodecanoyl homologue. Evidence was obtained that a third syringomycin-producing strain and a syringotoxin-producing strain synthesize 3-hydroxydecanoyl-Dhb-Pro-Val-Ala-Ala-Val-Leu-Ala-Ala-Dhb-Val-Dhb-Ala-Val-Ala-Ala-Dhb-aThr-Ser-Ala-Val-Ala-Dab-Dab-Tyr, with Tyr and aThr forming again the macrolactone ring, and smaller amounts of the 3-hydroxydodecanoyl homologue.

引用

页码：109 / 112

页数：4

共 25 条

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