SYNTHESIS AND PROPERTIES OF FIRST-GENERATION TO 3RD-GENERATION DENDRIMERS WITH DOUBLY AND TRIPLY BRANCHED CHIRAL BUILDING-BLOCKS

被引：61

作者：

MURER, P ^{[1
]}

SEEBACH, D ^{[1
]}

机构：

[1] ETH ZENTRUM,ORGAN CHEM LAB,CH-8092 ZURICH,SWITZERLAND

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 19期

关键词：

ASYMMETRIC SYNTHESES; CHIRAL DENDRIMERS; CIRCULAR DICHROISM; DENDRIMERS; MASS SPECTROMETRY;

D O I：

10.1002/anie.199521161

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dendrimers with chiral branch components and chiral central units display remarkable CD effects. An interesting case of diastereoselectivity occurs in the synthesis of these compounds: The branch bromide 1 with (S) configuration at the four nonspecific centers can be coupled with the triol 2; the (R) branch bromide 1, on the other hand, cannot! (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：2116 / 2119

页数：4

共 22 条

[1] (E,R,R)-5-ALKYLIDENE-2-TERT-BUTYL-6-METHYL-1,3-DIOXAN-4-ONES - PREPARATION FROM (R)-3-HYDROXYBUTYRIC ACID, CUPRATE ADDITIONS, AND HYDROLYZES TO 3-HYDROXYCARBOXYLIC ACIDS WITH CHIRAL SECONDARY ALKYL SUBSTITUENTS IN THE 2-POSITION
AMBERG, W
SEEBACH, D
[J]. CHEMISCHE BERICHTE, 1990, 123 (12) : 2413 - 2428
[2] ENANTIOSELECTIVE CATALYSIS .85. OPTICALLY-ACTIVE EXPANDED CHELATE PHOSPHINES DERIVED FROM 1,OMEGA-BIS(DICHLOROPHOSPHINO)ALKANES
BRUNNER, H
FURST, J
[J]. TETRAHEDRON, 1994, 50 (15) : 4303 - 4310
[3] SYNTHESIS AND CHARACTERIZATION OF OPTICALLY-ACTIVE, HOMOCHIRAL DENDRIMERS
CHOW, HF
FOK, LF
MAK, CC
[J]. TETRAHEDRON LETTERS, 1994, 35 (21) : 3547 - 3550
[4] PREPARATION OF POLYMERS WITH CONTROLLED MOLECULAR ARCHITECTURE - A NEW CONVERGENT APPROACH TO DENDRITIC MACROMOLECULES
HAWKER, CJ
FRECHET, JMJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (21) : 7638 - 7647
[5] ISSBERNER J, 1994, ANGEW CHEM INT EDIT, V33, p241P
[6] ISSBERNER J, 1994, ANGEW CHEM, V106, P2507
[7] JANSEN JFG, 1995, ANGEW CHEM, V107, P1321
[8] OPTICAL-ACTIVITY OF CHIRAL DENDRITIC SURFACES
JANSEN, JFGA
PEERLINGS, HWI
DEBRABANDERVANDENBERG, EMM
MEIJER, EW
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1995, 34 (11): : 1206 - 1209
[9] PREPARATION OF CHIRAL BUILDING-BLOCKS FOR STARBURST DENDRIMER SYNTHESIS
LAPIERRE, JM
SKOBRIDIS, K
SEEBACH, D
[J]. HELVETICA CHIMICA ACTA, 1993, 76 (07) : 2419 - 2432
[10] Nakanishi K., 1994, CIRCULAR DICHROISM

← 1 2 3 →