Dystrophin and the membrane skeleton

被引：132

作者：

Ervasti, James M. ^{[1
]}

Campbell, Kevin P. ^{[2
,3
]}

机构：

[1] Univ Wisconsin, Dept Physiol, Madison, WI 53706 USA

[2] Univ Iowa, Coll Med, Howard Hughes Med Inst, Iowa City, IA 52242 USA

[3] Univ Iowa, Coll Med, Dept Physiol & Biophys, Iowa City, IA 52242 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 01期

关键词：

D O I：

10.1016/S0955-0674(05)80012-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent studies have confirmed several predictions concerning the structure and possible function of dystrophin, including a direct interaction with F-actin and an indirect interaction with laminin via linkage through a transmembrane protein complex. The results of the past year support a role for dystrophin in linking the actin cytoskeleton with the extracellular matrix in striated muscle, but they have not explained its function in other tissues.

引用

页码：82 / 87

页数：6

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