机构:
Univ Wisconsin, Dept Physiol, Madison, WI 53706 USAUniv Wisconsin, Dept Physiol, Madison, WI 53706 USA
Ervasti, James M.
[1
]
Campbell, Kevin P.
论文数: 0引用数: 0
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机构:
Univ Iowa, Coll Med, Howard Hughes Med Inst, Iowa City, IA 52242 USA
Univ Iowa, Coll Med, Dept Physiol & Biophys, Iowa City, IA 52242 USAUniv Wisconsin, Dept Physiol, Madison, WI 53706 USA
Campbell, Kevin P.
[2
,3
]
机构:
[1] Univ Wisconsin, Dept Physiol, Madison, WI 53706 USA
[2] Univ Iowa, Coll Med, Howard Hughes Med Inst, Iowa City, IA 52242 USA
[3] Univ Iowa, Coll Med, Dept Physiol & Biophys, Iowa City, IA 52242 USA
Recent studies have confirmed several predictions concerning the structure and possible function of dystrophin, including a direct interaction with F-actin and an indirect interaction with laminin via linkage through a transmembrane protein complex. The results of the past year support a role for dystrophin in linking the actin cytoskeleton with the extracellular matrix in striated muscle, but they have not explained its function in other tissues.