CHIRAL PHOSPHANODIHYDROOXAZOLES IN ASYMMETRIC CATALYSIS - TUNGSTEN-CATALYZED ALLYLIC SUBSTITUTION

被引：215

作者：

LLOYDJONES, GC ^{[1
]}

PFALTZ, A ^{[1
]}

机构：

[1] UNIV BASEL,INST ORGAN CHEM,CH-4056 BASEL,SWITZERLAND

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 04期

关键词：

ALKYLATIONS; ASYMMETRIC SYNTHESES; CATALYSIS; DIHYDROOXAZOLES; TUNGSTEN COMPOUNDS;

D O I：

10.1002/anie.199504621

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Enantiomeric excesses up to 96% have been obtained in allylic alkylations of 3‐aryl‐2‐propenyl phosphates 2 to give 3 with CH(CO2Me) 2− as nucleophile Nu− by using a new tungsten catalyst derived from the phosphanodihydrooxazole complex 1 (X = CH3CN). The regioselectivity is opposite to that of analogous Pd‐catalyzed reactions. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：462 / 464

页数：3

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