A SIMPLE METHOD FOR N-15 LABELING OF EXOCYCLIC AMINO-GROUPS IN SYNTHETIC OLIGODEOXYNUCLEOTIDES

被引：42

作者：

ACEDO, M

FABREGA, C

AVINO, A

GOODMAN, M

FAGAN, P

WEMMER, D

ERITJA, R

机构：

[1] CSIC,CID,DEPT MOLEC GENET,E-08034 BARCELONA,SPAIN

[2] UNIV SO CALIF,DEPT BIOL SCI,LOS ANGELES,CA 90089

[3] UNIV CALIF BERKELEY,DEPT CHEM,BERKELEY,CA 94720

来源：

NUCLEIC ACIDS RESEARCH | 1994年 / 22卷 / 15期

关键词：

D O I：

10.1093/nar/22.15.2982

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The use of the ammonia deprotection step to introduce N-15 labels at specific exocyclic amino positions of adenine, cytosine, guanine or 2-aminopurine of oligodeoxynucleotides is described.

引用

页码：2982 / 2989

页数：8

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