AN EFFICIENT SYNTHESIS OF DIETHYL 1-AMINOALKYLPHOSPHONATE HYDROCHLORIDES VIA THE INTERMEDIATE DIETHYL 1-AZIDOALKYLPHOSPHONATES

被引：38

作者：

GAJDA, T

MATUSIAK, M

机构：

[1] Institute of Oragnic Chemistry, Technical University, Zwirki 36

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 15期

关键词：

D O I：

10.1080/00397919208019072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compounds 4 have been obtained in high yields in a one-step sequence by the Mitsunobu reaction of diethyl 1-hydroxyalkylphosphonates 1 with hydrazoic acid, and subsequence treatment of the intermediate azides 2 with triphenylphosphine, followed by hydrolysis of the iminophosphoranes 3 with water.

引用

页码：2193 / 2203

页数：11

共 30 条

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