THE ROLE OF EPSTEIN-BARR-VIRUS SUBTYPES IN HUMAN IMMUNODEFICIENCY VIRUS-ASSOCIATED LYMPHOMA

被引：12

作者：

BOYLE, MJ ^{[1
]}

SCULLEY, TB ^{[1
]}

PENNY, R ^{[1
]}

SEWELL, WA ^{[1
]}

TSCHUCHNIGG, M ^{[1
]}

BERGER, MF ^{[1
]}

COOPER, DA ^{[1
]}

机构：

[1] ST VINCENTS HOSP,CTR IMMUNOL,SYDNEY,NSW 2010,AUSTRALIA

来源：

LEUKEMIA & LYMPHOMA | 1993年 / 10卷 / 1-2期

关键词：

HIV-ASSOCIATED LYMPHOMA; EBV; EBV SUBTYPES; HUMAN IMMUNODEFICIENCY VIRUS;

D O I：

10.3109/10428199309147352

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

High grade B cell non-Hodgkin's lymphoma (NHL) is an increasingly important problem in individuals infected with the human immunodeficiency virus (HIV). Fifty percent of these tumours harbour the Epstein-Barr virus (EBV) and there is an equal frequency of EBV A and B-subtypes in the tumours. This contrasts with the recent report that only A-type EBV is associated with Hodgkin's disease. Such studies are challenging the traditional models of EBV-associated lymphomagenesis and showing the way for further studies in this field. This article reviews the studies of EBV subtypes in HIV-associated NHL and uses this new knowledge to discuss the role of EBV in lymphomagenesis.

引用

页码：17 / 23

页数：7

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