POTENTIAL TARGETS FOR AUTOSOMAL SCID MUTATIONS

被引：29

作者：

TACCIOLI, GE ^{[1
]}

ALT, FW ^{[1
]}

机构：

[1] HARVARD UNIV, SCH MED, DEPT GENET, BOSTON, MA USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 04期

关键词：

D O I：

10.1016/0952-7915(95)80085-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Significant advances have been recently made in the molecular characterization of genes that encode proteins with activities that are directly, or indirectly, involved in the assembly of antigen receptor variable region genes. Such genes are candidate targets for human autosomal mutations that lead to severe combined immune deficiencies characterized by a lack of both T and B cells.

引用

收藏

页码：436 / 440

页数：5

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