甲烷氧化菌及甲烷单加氧酶的研究进展

被引：38

作者：

韩冰 ^{[1
]}

苏涛 ^{[2
]}

李信 ^{[2
]}

邢新会 ^{[1
]}

机构：

[1] 清华大学化工系生物化工研究所

[2] 中国农业科学院研究生院

来源：

生物工程学报 | 2008年 / 09期

关键词：

甲烷氧化菌; 甲烷单加氧酶; 甲烷; 分子生物学; 工业生物技术;

D O I：

10.13345/j.cjb.2008.09.001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

甲烷氧化菌是以甲烷作为唯一碳源和能源进行同化和异化代谢的微生物,其关键酶之一是甲烷单加氧酶(MMOs),可以在氧气的作用下催化甲烷等低碳烷烃或烯烃羟基化或环氧化,甲烷氧化菌在自然界碳循环和工业生物技术中具有重要的应用价值。因此,近20年来对于甲烷氧化菌和MMOs的研究一直倍受生物学家的关注。以下从现代生物技术的角度,对近年来国内外在甲烷氧化菌的分类与分布,MMOs的结构与功能、甲烷氧化菌与MMOs的基因工程等方面取得的研究成果进行了总结,全面综述了甲烷氧化菌及MMOs的应用基础研究现状,并对其今后的研究和应用方向提出了展望。

引用

页码：1511 / 1519

页数：9

共 22 条

[11]

Raquel L. Lieberman,Amy C. Rosenzweig.Biological Methane Oxidation: Regulation, Biochemistry, and Active Site Structure of Particulate Methane Monooxygenase[J].Critical Reviews in Biochemistry and Molecular Bi,2004(3)

[12]

Daniel A Kopp,Stephen J Lippard.Soluble methane monooxygenase: activation of dioxygen and methane[J].Current Opinion in Chemical Biology,2002(5)

[13]

Marina Kaluzhnaya,Valentina Khmelenina,Bulat Eshinimaev,Natalia Suzina,Dimitry Nikitin,Alexander Solonin,Ju-Ling Lin,Ian McDonald,Colin Murrell,Yuri Trotsenko.Taxonomic Characterization of New Alkaliphilic and Alkalitolerant Methanotrophs from Soda Lakes of the Southeastern Transbaikal Region and description of Methylomicrobium buryatense sp.nov[J].Systematic and Applied Microbiology,2001(2)

[14] Regulation of expression of methane monooxygenases by copper ions [J].

Murrell, JC ;

McDonald, IR ;

Gilbert, B .

TRENDS IN MICROBIOLOGY, 2000, 8 (05) :221-225

[15] An obligate methylotrophic, methane-oxidizing Methylomicrobium species from a highly alkaline environment [J].

Sorokin, DY ;

Jones, BE ;

Kuenen, JG .

EXTREMOPHILES, 2000, 4 (03) :145-155

[16] Molecular biology and regulation of methane monooxygenase [J].

J. Colin Murrell ;

Bettina Gilbert ;

Ian R. McDonald .

Archives of Microbiology, 2000, 173 :325-332

[17]

Marina G. Kalyuzhnaya,Valentina N. Khmelenina,Svetlana Kotelnikova,Louise Holmquist,Karsten Pedersen,Yuri A. Trotsenko.Methylomonas scandinavica sp.nov., a New Methanotrophic Psychrotrophic Bacterium isolated from Deep Igneous Rock Ground Water of Sweden[J].Systematic and Applied Microbiology,1999(4)

[18] Heterologous expression of soluble methane monooxygenase genes in methanotrophs containing only particulate methane monooxygenase [J].

Lloyd, JS ;

De Marco, P ;

Dalton, H ;

Murrell, JC .

ARCHIVES OF MICROBIOLOGY, 1999, 171 (06) :364-370

[19]

Levente Bodrossy,E. M. Holmes,A. J. Holmes,Kornél L. Kovács,J. C. Murrell.Analysis of 16S rRNA and methane monooxygenase gene sequences reveals a novel group of thermotolerant and thermophilic methanotrophs, Methylocaldum gen. nov[J].Archives of Microbiology,1997(6)

[20] Isolation and Characterization of Halotolerant Alkaliphilic Methanotrophic Bacteria from Tuva Soda Lakes [J].

Valentina N. Khmelenina ;

Marina G. Kalyuzhnaya ;

Natalia G. Starostina ;

Natalia E. Suzina ;

Yuri A. Trotsenko .

Current Microbiology, 1997, 35 :257-261

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