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肠道菌群紊乱与粪菌移植

被引：66
作者：
李宁
机构：
[1] 南京大学医学院临床学院(南京军区南京总医院)解放军普通外科研究所
来源：
肠外与肠内营养 | 2014年 / 21卷 / 04期
关键词：
肠道菌群; 粪菌移植; 难辨梭菌感染; 炎症性肠病; 治疗;
D O I：
10.16151/j.1007-810x.2014.04.015
中图分类号：
R574.4 [肠道功能紊乱];
学科分类号：
100201 [内科学];
摘要：
<正>肠道微生物生态系统是哺乳动物体内最复杂和最大的微生态系统,肠道菌群种类多达1 000余种,细菌总数多达100万亿,是宿主细胞数量的10倍。其主要由硬壁菌门、拟杆菌门、放线菌门和变形杆菌门构成,其中严格厌氧菌的数量比兼性厌氧菌和需氧菌多2～3个数量级[1]。不同个体消化道中存在主导菌群,采用宏基因组学高通量测序方法可划分为拟杆菌属型、普氏菌属型、瘤胃球菌属型三种不同的"肠类型"。根据菌群代谢途径的特点,摄高蛋白
引用
收藏
页码：193 / 197
页数：5
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