β-环糊精包合物的结构研究

The inclusion complexes of β-cyclodextrin(β-CD) with vanillin, sebacic acid and cholesterol were prepared. DSC analysis showed that the optimum qualitative ratio of three inclusion complexes was 1∶1, 2∶1, 3∶1, respectively. XRD results of β-CD and its inclusion complexes indicate that the crystals of three inclusion complexes belong to an obvious channel-type packing structure, and the axial structure period is two times of the height of β-CD torus. The structural models of three inclusion complexes were proposed according to "head-head" alignment of β-CDs, molecular size match and polarity. A specific peak in XRD spectra indication of forming inclusion complex can be identified at 1 2 nm(about 7 degrees).