多模医学图像引导的非小细胞肺癌放疗研究新进展

被引：5

作者：

张书旭

林生趣

机构：

[1] 广州医科大学附属肿瘤医院放疗中心

来源：

癌症进展 | 2013年 / 11卷 / 06期

基金：

广东省科技计划;

关键词：

多模医学图像引导; 非小细胞肺癌; 放疗;

D O I：

暂无

中图分类号：

R734.2 [肺肿瘤];

学科分类号：

100117 [系统生物医学];

摘要：

放射治疗是目前非小细胞肺癌的主要治疗手段之一,在放疗过程中,利用功能影像与CT解剖影像相结合,不但提高了肿瘤靶区的勾画精度,而且,还能利用功能影像显示的靶区细胞的生物学特性,进行生物功能图像引导的剂量雕刻(dosepainting)治疗,这是放射治疗发展过程的一个重要转折点。对局部晚期非小细胞肺癌而言,采用累及野照射的方式优于选择性淋巴结照射。利用4D-CT图像引导的个体化靶区勾画、锥形束CT(cone beam CT,CBCT)图像引导放疗和自适应放疗(adaptive radiation therapy,ART)技术的应用,进一步提高了非小细胞肺癌放疔的精度,可望减少放射性肺炎等正常组织损伤、提高肿瘤控制率和改善疗后生存质量。

引用

页码：520 / 524

页数：5

共 29 条

[1]

State of the Art Radiation Therapy for Lung Cancer 2012: A Glimpse of the Future.[J]..Clinical Lung Cancer.2012,

[2]

CONE-BEAM COMPUTED TOMOGRAPHIC IMAGE GUIDANCE FOR LUNG CANCER RADIATION THERAPY [J].

Bissonnette, Jean-Pierre ;

Purdie, Thomas G. ;

Higgins, Jane A. ;

Li, Winnie ;

Bezjak, Andrea .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 73 (03) :927-934

[3]

Tumor biology-guided radiotherapy treatment planning: Gross tumor volume versus functional tumor volume [J].

Guha, Chandan ;

Alfieri, Alan ;

Blaufox, M. Donald ;

Kalnicki, Shalom .

SEMINARS IN NUCLEAR MEDICINE, 2008, 38 (02) :105-113

[4]

Interfractional changes in tumour volume and position during entire radiotherapy courses for lung cancer with respiratory gating and image guidance [J].

Juhler-Nottrup, Trine ;

Korreman, Stine S. ;

Pedersen, Anders N. ;

Persson, Gitte F. ;

Aarup, Lasse R. ;

Nystrom, Hakan ;

Olsen, Mikael ;

Tarnavski, Nikolai ;

Specht, Lena .

ACTA ONCOLOGICA, 2008, 47 (07) :1406-1413

[5]

Intrathoracic Patterns of Failure for Non–Small-Cell Lung Cancer With Positron-Emission Tomography/Computed Tomography–Defined Target Delineation.[J].Ann Hoge Klopp;Joe Y. Chang;Susan L. Tucker;Erik P. Sulman;Peter A. Balter;H. Helen Liu;M. Kara Bucci;Homer A. Macapinlac;Ritsuko Komaki;James D. Cox.International Journal of Radiation Oncology; Biology; Physics.2007, 5

[6]

Assessment of Gross Tumor Volume Regression and Motion Changes During Radiotherapy for Non–Small-Cell Lung Cancer as Measured by Four-Dimensional Computed Tomography.[J].Keith R. Britton;George Starkschall;Susan L. Tucker;Tinsu Pan;Christopher Nelson;Joe Y. Chang;James D. Cox;Radhe Mohan;Ritsuko Komaki.International Journal of Radiation Oncology; Biology; Physics.2007, 4

[7]

Kilo-voltage cone-beam computed tomography setup measurements for lung cancer patients; First clinical results and comparison with electronic portal-imaging device [J].

Borst, Gerben R. ;

Sonke, Jan-Jakob ;

Betgen, Anja ;

Remeijer, Peter ;

Van Herk, Marcel ;

Lebesque, Joos V. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 68 (02) :555-561

[8]

Initial Evaluation of Treatment-Related Pneumonitis in Advanced-Stage Non–Small-Cell Lung Cancer Patients Treated With Concurrent Chemotherapy and Intensity-Modulated Radiotherapy.[J].Sue S. Yom;Zhongxing Liao;H. Helen Liu;Susan L. Tucker;Chao-Su Hu;Xiong Wei;Xuanming Wang;Shulian Wang;Radhe Mohan;James D. Cox;Ritsuko Komaki.International Journal of Radiation Oncology; Biology; Physics.2007, 1

[9]

Analysis of clinical and dosimetric factors associated with treatment-related pneumonitis (TRP) in patients with non–small-cell lung cancer (NSCLC) treated with concurrent chemotherapy and three-dimensional conformal radiotherapy (3D-CRT).[J].Shulian Wang;Zhongxing Liao;Xiong Wei;Helen H. Liu;Susan L. Tucker;Chao-su Hu;Rodhe Mohan;James D. Cox;Ritsuko Komaki.International Journal of Radiation Oncology; Biology; Physics.2006, 5

[10]

A technique for adaptive image-guided helical tomotherapy for lung cancer [J].

Ramsey, CR ;

Langen, KM ;

Kupelian, PA ;

Scaperoth, DD ;

Meeks, SL ;

Mahan, SL ;

Seibert, RM .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 64 (04) :1237-1244

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