肠上皮内淋巴细胞及其免疫学进展

被引：13

作者：

方芳

陈冬梅

张博芬

机构：

[1] 沈阳医学院医学基础部微生物与免疫教研室

[2] 沈阳医学院医学基础部微生物与免疫教研室辽宁沈阳

[3] 辽宁沈阳

来源：

沈阳医学院学报 | 2004年 / 02期

关键词：

肠上皮内淋巴细胞; 细胞因子; 口服耐受;

D O I：

暂无

中图分类号：

R392.1 [免疫生物学];

学科分类号：

100108 [医学免疫学];

摘要：

<正> 上皮内淋巴细胞(intraepithelial lymphocyte,IEL)广泛分布在皮肤、呼吸道、胃肠道及泌尿生殖道。肠上皮内淋巴细胞(intestinal intraepithelial lymphocyte,iIEL)定位于肠上皮细胞(intestinal epithelialcell,IEC)间,正常成人平均每100个IEC间有6-40个iIEL。iIEL与IEC紧密接触且与含有多种抗原的局部微环境密切相关,均表明其具有黏膜免疫功能。本文就目前对iIEL发育、作用机理及在肠道疾病、口服耐受作用中的研究进展综述如下。

引用

页码：121 / 124

页数：4

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