神经干细胞治疗阿尔茨海默病的研究进展

被引：3

作者：

蔡志友 ^{[1
]}

晏勇 ^{[1
]}

唐勇 ^{[2
]}

王咏龙 ^{[1
]}

吴芳 ^{[1
]}

机构：

[1] 重庆医科大学附属第一医院神经内科重庆市神经病学重点实验室

[2] 重庆医科大学科研处

来源：

生命科学 | 2008年 / 01期

关键词：

阿尔茨海默病; 神经干细胞; 治疗;

D O I：

暂无

中图分类号：

R749.16 [];

学科分类号：

100203 ;

摘要：

神经干细胞(neural stem cell,NSCs)为阿尔茨海默病(Alzheimer’s disease,AD)神经系统的损伤修复和治疗提供了一个崭新的手段,具有广阔的应用前景。NSCs治疗AD的目的是修复和替代受损的神经细胞,重建细胞环路和细胞功能,主要通过两种途径:内源性途径,即诱导内源性NSC增殖与分化;外源性途径,即直接替代缺损组织或植入基因工程细胞,使受损伤的中枢神经系统修复。NSCs给AD的治疗带来了希望,如何诱导脑内的内源性NSCs增殖并分化为神经元形成功能网络是今后AD治疗的重要研究方向。

引用

页码：90 / 94

页数：5

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