凋亡与自噬的相互关系在类风湿关节炎中的研究进展

被引：13

作者：

李春莳

孙英焕

杜明

陶李

李光迪

机构：

[1] 兰州大学第二医院

来源：

风湿病与关节炎 | 2017年 / 6卷 / 10期

关键词：

关节炎,类风湿; 凋亡; 自噬; p53; Beclin1; TNF-α; p62; 综述;

D O I：

暂无

中图分类号：

R593.22 [类风湿性关节炎];

学科分类号：

100201 [内科学];

摘要：

凋亡和自噬作为程序性细胞死亡的两种形式,二者相互联系又相互区别,凋亡和自噬的异常状态与类风湿关节炎的发生、发展密切相关。对于二者相互作用的研究不仅可以进一步揭示类风湿关节炎发生、发展的潜在机制,而且为其治疗和预防提供了新的思路。结合近年来国内外研究进展,就凋亡与自噬的相互关系在类风湿关节炎中的作用进行综述。

引用

页码：65 / 68

页数：4

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