凝视、面、臂、言语、时间评分对急性前循环大动脉闭塞性卒中的预测价值

被引:2
作者
张运
王莉莉
机构
[1] 首都医科大学附属北京世纪坛医院神经内科
关键词
急性缺血性卒中; 前循环大动脉闭塞; G-FAST评分; 血管内治疗; 受试者工作特征曲线;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
目的 探讨凝视、面、臂、言语、时间(G-FAST)评分早期识别急性前循环大动脉闭塞性卒中的准确性。方法 回顾性纳入2012年5月至2018年4月期间连续就诊首都医科大学附属北京世纪坛医院具有完整的发病6 h内血管影像资料的前循环梗死病例。以数字减影血管造影(DSA)或CT血管成像(CTA)判定的有无急性前循环大动脉闭塞结果为参照标准,分为有大动脉闭塞组与无大动脉闭塞组。利用受试者工作特征曲线(ROC)下的面积(AUC)分析G-FAST评分判定急性前循环大动脉闭塞性卒中的准确度,并比较其与国立卫生院神经功能缺损评分(NIHSS)、Alberta卒中早期CT评分(ASPECTS)对前循环大动脉闭塞的预测价值。结果 研究纳入138例急性前循环缺血性卒中病例(其中82例有大动脉闭塞,占59.4%)。单因素分析显示有大动脉闭塞组的基线NIHSS评分(12.0比8.9,P=0.000),G-FAST评分(3.1比2.2,P=0.000)显著高于无大动脉闭塞组,ASPECTS显著低于无大动脉闭塞组(7.4比8.2,P=0.001)。ROC结果显示G-FAST评分,NIHSS评分及ASPECTS预测前循环大动脉闭塞的ROC曲线下面积分别为0.781,0.733,0.664,其中G-FAST评分的预测准确度最高。G-FAST评分预测前循环大动脉闭塞最佳界值为2.5分,其敏感度为79.3%,特异度为64.3%。进一步单因素分析显示G-FAST评分≥3分组的LAVO与G-FAST评分≤2分组比较存在显著差异[76.5%(65/85)比32.1%(17/53),P=0.000]。结论 G-FAST评分对急性前循环大动脉闭塞性卒中具有一定预测价值。G-FAST高分值患者在条件允许时可考虑尽早进行血管内治疗。
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页码:2302 / 2307
页数:6
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