LOTUS, a potent blocker of Nogo receptor-1 causing inhibition of axonal growth

被引:1
作者
Yuji Kurihara
Kohtaro Takei
机构
[1] MolecularMedicalBioscienceLaboratory,DepartmentofMedicalLifeScience,YokohamaCityUniversityGraduateSchoolofMedicalLifeScience,Suehiro-cho--,Tsurumi-ward,Yokohama-,Japan
关键词
OMgp; MAG; a potent blocker of Nogo receptor-1 causing inhibition of axonal growth; LOTUS;
D O I
暂无
中图分类号
R338.1 [神经原生理学];
学科分类号
0710 ; 071006 ;
摘要
<正>Glia-derived axonal growth inhibitory proteins limit functional repair following damage to the adult central nervous system(CNS).Nogo proteins,myelin-associated glycoprotein(MAG),oligodendrocyte myelin glycoprotein(OMgp)and B lymphocyte stimulator(BLy S),are 4 inhibitors that commonly interact with the neuronal receptor,Nogo receptor-1(Ng R1),leading to inhibition of axonal growth.Here,we demonstrate that lateral olfactory tract usher substance
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页码:46 / 48
页数:3
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