Ⅰ型胶原蛋白的结构、功能及其应用研究的现状与前景

被引:51
作者
张达江
王亮
机构
[1] 中国科学院新疆分院理化技术研究所
关键词
胶原蛋白; 生物反应器; 转基因;
D O I
暂无
中图分类号
Q51 [蛋白质];
学科分类号
071010 ; 081704 ;
摘要
胶原蛋白是动物体中普遍存在的一种大分子蛋白,在哺乳动物中的含量是整个生物体自身总蛋白含量的1/4。胶原蛋白除了具有生物力学方面的作用以外,还具有诸如信号转导、生长因子与细胞因子的运输等功能;此外,在食品、化妆品、医药等行业中,胶原蛋白也具有很广泛的用途。随着对胶原蛋白需求的日益增加,原先从屠宰的动物体的皮革、骨骼中提取胶原的方式已经不能满足日益增长的胶原蛋白的需求,而且还可能有致病之虞,于是新的生产胶原蛋白的方法——利用生物反应器,尤其是乳腺生物反应器来生产胶原蛋白就为人们所瞩目。本文就Ⅰ型胶原蛋白的结构、功能,以及利用生物反应器研究开发Ⅰ型胶原蛋白的现状、前景进行了探讨。
引用
收藏
页码:265 / 269
页数:5
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