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脓毒症与肠屏障功能关系的研究进展

被引：9
作者：
赵鹏
机构：
[1] 泰安市中心医院PICU
来源：
国际儿科学杂志 | 2019年 / 46卷 / 07期
关键词：
脓毒症; 肠屏障功能;
D O I：
暂无
中图分类号：
R459.7 [急症、急救处理];
学科分类号：
100231 [临床病理学];
摘要：
近年来脓毒症越来越受到人们的关注, 严重危害儿童生命健康。肠道作为最大的细菌储备库, 长期以来被认为是多脏器功能衰竭的始动器官。肠屏障功能的完整性、通过性及上皮细胞功能的改变与脓毒症紧密相关。脓毒症过程中肠道共生菌可发生毒力增加和多样性降低的改变, 导致宿主发生进一步病理改变。该文就脓毒症与肠屏障功能的关系及发病机制进行阐述。
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