急性脑梗死患者血浆Lp-PLA2和hs-CRP水平及意义

被引：19

作者：

朴海

金永华

机构：

[1] 哈尔滨医科大学附属第二医院神经内科

来源：

哈尔滨医科大学学报 | 2012年 / 46卷 / 03期

关键词：

急性脑梗死; 脂蛋白相关磷脂酶A2; 超敏C反应蛋白;

D O I：

暂无

中图分类号：

R743.33 [脑栓塞];

学科分类号：

1002 ;

摘要：

目的探讨血浆脂蛋白相关磷脂酶A2(lipoprotein-associated phospholipase A2,Lp-PLA2)及超敏C反应蛋白(high-sensitivity C-reactive protein,hs-CRP)水平与急性脑梗死患者脑梗死体积、神经功能缺损程度的关系。方法收集急性脑梗死患者(62例)和未卒中对照者(26例),采用酶联免疫吸附法检测血浆Lp-PLA2水平,免疫速率散射比浊法检测hs-CRP水平。计算脑梗死体积并行神经功能缺损程度评估。结果 Lp-PLA2水平随脑梗死体积增加而呈递增趋势,差异无统计学意义;hs-CRP水平随脑梗死体积增加而呈递增趋势,差异有统计学意义;Lp-PLA2及hs-CRP水平随神经功能缺损程度增加而呈递增趋势,差异有统计学意义;经相关性分析Lp-PLA2和hs-CRP水平无相关性。结论急性脑梗死患者血浆Lp-PLA2水平升高与神经功能缺损程度有关,而与脑梗死体积无关;hs-CRP水平升高与神经功能缺损程度及脑梗死体积有关。

引用

页码：266 / 269

页数：4

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