NLRP1和NLRP3炎性体的研究进展

被引:19
作者
原孟
尚丽新
机构
[1] 北京军区总医院妇产科
关键词
早产; 先天性免疫应答; NLRP1; NLRP3;
D O I
暂无
中图分类号
R363 [病理生理学];
学科分类号
100103 [病原生物学];
摘要
炎性体作为一种新近发现的蛋白质复合物,其活化后可促进炎性因子的成熟与释放,在先天性免疫中发挥着重要的作用。本文就核苷酸结合寡聚化结构域样受体蛋白1(NLRP1)和3(NLRP3)炎性体的构成、激活机制及信号传导通路和相关的疾病做出综述,并对NLRP1和NLRP3炎性体与早产的关系做出推测。
引用
收藏
页码:10894 / 10897
页数:4
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