透皮促渗方法联合应用的研究进展

被引:21
作者
王斐
高申
机构
[1] 上海第二军医大学药学院
关键词
透皮给药系统; 透皮吸收促进剂; 超声导入法; 离子导入法; 电穿孔法;
D O I
10.13220/j.cnki.jipr.2007.04.053
中图分类号
R94 [药剂学];
学科分类号
100702 [药剂学];
摘要
透皮给药系统具有传统给药方式不可比拟的优势。但由于药物的低渗透量,使其应用受到一定限制。各种物理的、化学的促渗方法,包括透皮吸收促进剂、超声导入法、离子导入法、电穿孔法等可改善皮肤透过性,增加药物的透皮速率。而且几种方法联合应用的促渗效果更加显著。本文总结了近年来各种促渗方法联合应用的研究进展。
引用
收藏
页码:285 / 289
页数:5
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